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As SM is no longer used as a first-line anti-TB drug in France [ 27], detecting resistance to this particular antibiotic allows for estimating the proportion of TB reactivation on the one hand if the patients are old and for assessing the rate of active transmission of these strains on the other hand if the patients are young.
To have a better in vivo representation of the potential of these complexes as latency reactivators, a test on reactivation on T cells will be important since HIV predominantly resides in resting memory CD4+ T cells [ 39].
In the case of Kdm5c, there is initial silencing, but then rapid reactivation on the Xi [ 27], whereas Otc has been shown to reactivate slowly with age [ 28].
2D stability back analyses were performed on the SW slope of a dormant landslide, in the Rječina River Valley, with the purpose to predict the possible reactivation, on the basis of landslide features present on the field.
Second, we did not include partial immunity into the model, which might have led us to underestimate the role of endogenous reactivation on the transmission of TB in Hong Kong.
But even this adjusted analysis showed no impact of CMV reactivation on mortality (Table 3).
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How protein disaggregation is achieved and whether survival is solely dependent on ClpB-mediated elimination of aggregates or also on reactivation of aggregated proteins has been unclear.
However, effect of HSV-2 reactivations on HIV disease progression markers in this population was modest and appears to be dependent on the frequency and severity of reactivations.
The influence of CMV-reactivation on the endpoints was analysed by Cox proportional-hazard regression analysis.
To evaluate the influence of CMV-reactivation on these endpoints we conducted uni- and multivariate Cox proportional-hazard regression analyses adjusting for confounding factors.
Another type of selective screening based on risk of viral reactivation (relying on the type of chemotherapy and cancer) is possible; more robust data are needed to determine the incidence and predictive factors for HBVR.
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