Slow and controlled hydration is essential as the first step in the reactivation of metabolic processes in the dry seed, leading to germination and growth.
The reactivation of this process is responsible for cell growth in more than 90% of basal cell carcinoma cases.
Fast rewarming rates have been shown to predict worse outcomes in animal models [ 49, 54, 55] due to the rapid reactivation of the inflammatory processes that were set-off by TH.
Polarization curves and impedance measurements made on non attacked welds, reference stainless steel and the metal covered by the exopolymer confirm that a reactivation of the corrosion process in previously damaged welded areas is produced.
In order to provide unequivocal proof that the PE-uni forms observed in the P. cynomolgi (or P. vivax) hepatic cultures are indeed hypnozoites, it would be necessary to observe after a suitable period of latency (at least 3 4 weeks), a reactivation of the maturation process that would lead to the release of merozoites.
In pathological conditions, EMT is considered as the reactivation of a developmental process controlled by a network of transcriptional regulators.
The temperature differences and the clinical signs of reactivation of the Charcot process were evaluated in 2 4-week intervals until the resolution stage was reached.
The prolonged incubation period already described in few muco-cutaneous leishmaniasis cases [ 11, 12] could suggest as primary option the endogenous reactivation of the infectious process promoted by the CS-induced impairment of the immune response.
Two or more complementary and non-redundant pathways could be targeted in sequence, to first induce autoimmune disease remission, and then restore a state of immune tolerance and prevent reactivation of the disease process.
Such investigation would be particularly useful for the analysis of the early changes occurring during the reactivation of normal nodule metabolic processes.
Once the inflammatory immune process has been interrupted, the second biologic would then be introduced to prevent reactivation of the autoimmune disease process such that the pathogenic cascade does not recur.
