Sentence examples for reactivation and development from inspiring English sources
Our objective was to systematically summarize and analyze evidence regarding HHV-6B reactivation and development of aGVHD.
An important question is for how long the latent stage of tuberculosis is continuing with a risk of reactivation and development of clinical disease.
Our analysis aimed to determine whether these data from the Norwegian experience after the Second World War can be used to estimate the duration of the latent stage and the associated risk of reactivation and development of clinical disease.
In light of their regulatory role, changes in the expression of Polyomavirus JC (JCPyV) microRNAs may be relevant for virus reactivation and the development of progressive multifocal leukoencephalopathy (PML).
Previously, we showed that acute MHV68 infection in IFNγR−/− mice was followed by virus reactivation and the development of progressive and multifocal fibrosis [8].
Experimental studies have shown that ganciclovir prevented murine CMV reactivation and the development of pulmonary fibrosis in immunocompetent mice with sepsis [ 42].
Thus, this latest study points to Ser-175 as an important target for HIV-1 reactivation and potential development of small molecule therapeutics.
Unlike the situation in humans, spontaneous reactivation and the development of recurrent lesions are rarely observed in mice (Hill et al., 1975; Feldman et al., 2002; Gebhardt & Halford, 2005).
Perturbation in the regulation of T cell control often triggers reactivation of HCMV and development of HCMV-associated diseases [17], [44], [45].
These results suggest that HHV-6 infection could augment JCV replication and, in the setting of natalizumab treatment, may have important implications for JCV reactivation and the subsequent development of PML.
Long-term follow-up of these patients is required to demonstrate an association between viral reactivation and subsequent tumour development, and thus confirm the potential oncogenic role of BKV.
