Sentence examples for reactivating agents from inspiring English sources

Thus, various p53 reactivating agents have been developed in order to restore its tumour suppressive abilities.

In view of this, p53 mutant reactivating agents have been developed.

The increase in the endogenous production of TNF-α by viral reactivating agents like the phorbol esters, PMA and prostratin was previously reported [ 16, 17], and is confirmed here for PMA.

Our reactivation assays suggested that when combined with prostratin, SAHA could be a more potent HIV-1 reactivating agent than VPA.

In view of this, novel p53-reactivating agents have been developed and these agents are relevant to the nature and pathology of MM.

Oxime compounds used in nerve agent antidote regimen reactivate nerve agent-inhibited AChE and halt the development of this cholinergic crisis.

2PAM reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent.

A subset of 4-PAM-halide co-polymers was designed to serve as a controlled release reservoir for N-hydroxyethyl 4-PAM (HE 4-PAM) molecules that reactivate nerve agent-inhibited acetylcholinesterase (AChE).

The multiplicity of mechanisms leading to HIV latency was also illustrated recently by the comparison of several latency-reactivating agents and their different efficiencies across latency models [ 26].

The gap between the successful viral particle production and viral transcription suggests that transcriptional latency cannot recapitulate all aspects of the viral reservoir and that other post-integration blocks exist, consistent with multiple recent studies using latency-reactivating agents and multiple models of HIV latency [ 23, 26, 32].

The introduction of genes can reactivate dormant infectious agents in the host cell or create new agents by recombination.