Sentence examples for reactivating activity from inspiring English sources

We used the EPISSAY system to determine if liposomal encapsulation enhanced the gene reactivating activity of decitabine.

Another supportive finding on their reactivating activity was the unexpected observation that the three post-treatment samples cluster together (Figures 4 and 5) when the four samples were compared with gene expression of normal breast.

EPISSAY could be a time-saving assay for screening compounds with gene reactivating activity.

Our results demonstrate that hydralazine is quite promising in regards to its gene demethylating and tumor suppressor gene reactivating activities without significant side effects.

The reactivated activity fraction represents enzyme forms that are partially oxidized by intracellular reactions with reactive oxygen species as well as artifactually by air exposure (Fig. 3).

We previously demonstrated that SIM+MET inhibit Akt phosphorylation and activity and reactivate AMPK activity in C4-2B cells; inhibition of Akt and activation of AMPK in cancer cells often leads to autophagy.

Numerous molecular inhibitors of Mdm2 are in various stages of development with the goal of reactivating p53 activity in cancer [ 20].

Knockdown of TSC2 indeed reactivated mTORC1 activity (represented by endogenous phospho-T389 p70S6K levels), but not mTORC2 activity (endogenous phospho-S473 Akt levels), in cells treated with rictor-specific siRNAs (Fig.  5B).

These results suggested that the activity of Eco1 was limiting in undamaged G2/M cells, and DNA damage response reactivated its activity.

MMP2 is known to be overexpressed in several cancers and tumor microvascular endothelial cells and has the ability to reactivate peptide activity by cleavage of the conjugate at the tumor site.

Our findings can be interpreted as the restoration of the p53-Hsp90α p53-Hsp90αn by PRinteractionncing the nuclear translocation of p53-Hsp90α and reactivating the transcriptional activity of p53.