Sentence examples for reactivate proliferation from inspiring English sources

An ongoing debate in relation to the treatment of metastatic breast cancer is whether to customize therapies that reactivate proliferation in dormant, circulating tumor cells and hence improve chemotherapeutic efficiency, or to maintain dormancy in these rogue cells [ 77, 78].

To rule out the possibility that these 'quiescent neuroblasts' were early in the differentiation pathway, we reasoned that if they were quiescent they could reactivate proliferation in a nourishing environment (Chell and Brand, 2010; Sousa-Nunes et al., 2010) whereas if they were differentiating they would never re-enter the cell cycle.

We found that nearly all of the neuroblasts that were quiescent at 12 hr after induction had reactivated proliferation and re-expressed progenitor markers.

The reversal of radiation-induced hematopoietic suppression relies on the survival of hematopoietic stem/progenitor cells and reactivated proliferation and differentiation.

To assess whether expression of RUNX2 in MDA-MB-231 cells is facilitated by protein stabilization, we reactivated proliferation in serum deprived MDA-MB-231 cells in the absence or presence of the protein synthesis inhibitor cycloheximide (100 μM).

Therefore, the use of pro-neurogenic therapies or approaches aimed at reactivating the proliferation of neural stem cells would restore the observed decline in neurogenesis at late stages of disease, providing a longer lasting repair response.

Quiescent neuroblasts reactivate and resume proliferation during larval stages, generating neurons that will contribute to the adult CNS (reviewed in Egger et al., 2008).

The developmental theory suggests that embryonic cells are trapped at the junction of the endochondrally ossified ethmoid bone with the membranously ossified frontal bone, and they reactivate with unregulated osseus proliferation.

Consistent with the reduced premature cellular senescence, VC treatment reactivated the cellular proliferation potential and upregulated the frequency of Ki67 positive cells (Fig. 2A and 2B).

After a period of mitotic dormancy, a specific subpopulation of NBs becomes reactivated and resumes proliferation in the larva (reviewed by Maurange and Gould, 2005).

This effect is enough to break the vicious cycle of production of proinflammatory cytokines and lacrimal lymphocyte proliferation, reactivating tears production to initiate the repair of the ocular surface, perhaps promoting regeneration of the acinar epithelial cells of the lacrimal gland.