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Only those inflammatory conditions with a clinically significant 'sustained' acute-phase reactant response are subject to the formation of amyloid.
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For example, pharmaceutical and nutritional factors that reduce inflammation and the ensuing acute-phase reactant responses could be employed to improve insulin sensitivity and delay disease onset.
To the best of our knowledge, this is the first study to investigate the pathophysiologic relevance of hepcidin in EONS and demonstrate increased levels of hepcidin in cord blood as an acute-phase reactant in response to sepsis.
The changes in the eluted reactant's response curves from a pulse reactor operated in Knudsen flow [e.g. a temporal-analysis-of-products (TAP) reactor] as a function of the pulse size was interpreted as due to varying fractional coverages of the catalyst surface.
Often regarded as an acute-phase reactant in response to physiologic stress, haptoglobin levels have been utilized in algorithms to aid in the diagnosis of sepsis [ 25, 28]; however evidence to suggest that haptoglobin and hemopexin levels are associated with clinical outcomes in patients with sepsis beyond their properties as acute-phase reactants is lacking.
On the other hand when the signal exceeds a threshold, whereby the forward reaction is now stronger than the backward reaction, the output of the module is one corresponding to essentially complete conversion of reactant X into response X∗.
Fibrinogen is synthesized in the liver and secreted into the circulation, and the levels of this acute-phase reactant increase in response to most forms of tissue injury, infection, or inflammation [ 24, 25].
k ) Zeroth reactant order reaction.
The dynamic response of reactant concentrations in both phases is simulated using a simulation language operating in the Laplace domain.
The dynamic response of reactant conversion is very nonlinear and unconventional, but the response of product purity is well approximated by a linear first-order differential equation.
Multiple plasma proteins, including acute phase reactants, structural proteins, immune response proteins, coagulation and transcriptional factors, were differentially expressed similarly among the different SAID studied.
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