For the delineation of GTVPET, we performed the same procedure as employed by Astner et al. [ 14], defining tumour borders by adapting the windowing to reach an alignment of the PET and MRI data.
It iteratively swaps the edges in an alignment until reaching an optimum (Chindelevitch et al., 2013).
We show that the optimal design is a compromise between the mean time to reach a perfect alignment between the two molecules and the stability of the complex.
In each case, we compared the mean time for the ODN to reach a perfect alignment with the target dsDNA, as well as the stability of the complex.
However the time necessary for the two DNA molecules to reach a first alignment is not the only relevant parameter for efficient repair.
In Cottonwood, the highway follows the old alignment of Cottonwood Street before reaching an intersection with Main Street.
However, it increases with torsional stresses applied on preloaded samples, reaching a maxima at a certain number of turns that corresponds to the maximum alignment of vector components.
A ratio of 212 DMPC molecules per cytochrome b5 is necessary to reach a quality of alignment that is comparable to pure DMPC/DHPC bicelle samples (see Figure 6D).
In terms of correctly aligned RI pairs, our multi-view alignment reaches a 99.7% performance.
