Exact(1)
However, after the dose limitation for norepinephrine had been reached, MAP and systemic vascular resistance index fell significantly below ST values in all groups (10 hours: P < 0.05 versus ST each; Table 1).
Similar(58)
Startups attacking high MAP problems must invest more time and capital into acquiring enough data to reach MAP and launch. .
Thus, reaching MAP values higher than 71±± 6 mm Hg could have no beneficial effect on tissue perfusion.
Tempol administration did not modify MAP levels in NS animals but normalized MAP in the HS-T group, reaching MAP levels very similar to those observed in NS rats (mmHg; NS-T: 97 ± 2 versus HS-T: 95 ± 3†) * P < 0.05 versus respective NS group, † P < 0.05 versus respective group without tempol.
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Fluid administration was stopped when MAP reached a predetermined goal (generally MAP >65 mmHg, and/or MAP and/or stroke volume increase >10 15 % compared to baseline) and/or central venous pressure increased >15 mmHg.
Seventy anesthetized male Wistar rats were submitted to femoral artery and vein catheterization for mean arterial pressure (MAP) measurement and blood withdrawal to reach a MAP of 40 mmHg.
After fluid resuscitation failed to improve MAP, a norepinephrine infusion was adjusted to reach a MAP of 65 mmHg in all patients.
After basal measurements at a MAP of 65 mmHg, norepinephrine was titrated to reach a MAP of 75 mmHg, and then to 85 mmHg.
Mice groups differed from their resuscitation between the 60th and the 120th minute: a fluid resuscitated group (FR) with NaCl 0,9% to reach a MAP level of 60 mmHg and a group resuscitated with fluid and norepinephrine (FRNE) to reach a MAP level of 60 mmHg.
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