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Because the Maya priests had reached advanced knowledge of astronomical phenomena and a sophisticated concept of time, it appears that their esoteric doctrines differed widely from the popular myths.
Therefore even when my older brother and I had reached advanced middle age, our father had died and our mother's health had declined to such an extent that she could no longer go to Bronxville, we held the yearly lunches in a private hotel dining room and had them replicate the exact menu we made for Mary in Bronxville.
Tumors in the pancreas typically don't cause major symptoms until the cancer has already reached advanced stages.
Unfortunately, most patients are diagnosed when the extrahepatic bile duct is already atretic and the liver has reached advanced fibrosis.
Those results suggest that under this time/temperature conditions (60 °C, 3 days) MR reached advanced stages.
Two other compounds (cetilistat, a monotherapy, and tesofensine, a polytherapy) have reached advanced Phase III testing but have not at the time of writing been formally submitted for approval in the USA or Europe.
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The problem can only get worse as the baby boomers reach advanced age.
He is determined to reach advanced proficient again on next year's test.
Hypertrophic cardiomyopathy (HCM) may remain clinically silent and undiagnosed until patients reach advanced age.
Despite the tremendous progress made in the management of heart failure (HF), many patients reach advanced stages.
Virtually everyone agrees that as people reach advanced age their reflexes slow, their vision deteriorates and their strength, agility and coordination may diminish.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com