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The levels of two of the MDSC subsets, prior to vaccination, were significantly correlated with overall survival (OS) (67), thus highlighting the importance of monitoring the levels of these cells and, indirectly, the need to reach harmonization in the field.
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Nevertheless, the administration hopes to eventually reach a harmonization agreement with affiliated sites to ensure that the same minimum set of protections for postdocs is in place at each institution.
Had this been done in concomitance with the initial proposal of 'substantial equivalence' - based regulation in the early '90s, stakeholders might have been better informed, and the final harmonization reached earlier.
NORMAN has also proven to be a good platform to reach consensus among experts for harmonization of practices.
To reach an international standardization and harmonization in the use of QIBs in multicentre clinical studies, producing high-quality reliable results, it is paramount to ensure prospective QC in the execution of the imaging protocol and obligatory compliance with the specified parameters.
An international methodological standardization and harmonization effort would contribute to reaching more solid evidence on the epigenetic impact of environmental stressors.
Worldwide research has now reached a level of integration where an effort towards the harmonization of procedures is absolutely needed.
Neither Valencia nor DC Comics could be reached for comment on the issue while the Spain-based Office for Harmonization in the Internal Market said it did not comment on individual cases.
Although SUVmean may be used for harmonization because of being unsusceptible to image noise, it never reached the uptake value of 4 even for the largest sphere (37 mm) due to partial volume effect.
Further harmonization of the chemicals legislation in Europe was done in 2007 by "REACH" ("Registration, Evaluation, Authorisation of Chemicals") entering into force.
A code book (harmonization guidelines) was made explaining how the variables were harmonized (see additional file 1: Harmonization guidelines).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com