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Moreover, whatever technology is used for screening, it is important to point out that the key for success is to reach a high coverage.
As r were >0.9 for all strains (acceptable technical variation, see Additional file 7: Figure S1), technical replicates were pooled for further analyses, in order to reach a high coverage per transcript and per SNP position.
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In this study, we combined two fundamental and complementary techniques, gas chromatography coupled to time-of-flight-mass spectrometry (GC-TOF-MS) and ultra-performance liquid chromatography coupled to high resolution fourier transformation mass spectrometry (LC-FT-MS), to reach a higher coverage of the metabolome (Fig. 1).
Active screening programs seem to be better able than passive screening programs to reach a higher coverage of hearing aids services in the community, and whether this is worth the slightly higher costs is a matter of judgment.
However, the former carries the benefit that it seems able to reach a higher coverage of hearing aids services and it can be combined with the screening and management of other diseases in the community.
Active screening and provision of hearing aids at the secondary care level is slightly more costly than passive screening and fitting of hearing aids at the tertiary care level, but seems also able to reach a higher coverage of hearing aids services.
The large amount of data provided the first guarantee for reaching a high coverage of locust genes.
Comparative genomic hybridisation has reached a high coverage of the target sequences and become more widely used.
To reach a high level of vaccination coverage worldwide, organizations such as Unicef now advocate enhancing trust in immunization by, among other things, seeking partnership with religious leaders and groups [ 4].
So a heat stable S. aureus vaccine could achieve a high coverage even in the hard to reach areas of the developing countries.
Reach a high level with all classes.
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