Future prospective studies on outcomes, possibility of swallow re-evaluation, effect on family and patient decision making, and application to healthcare costs are encouraged.
Yet significant shortcomings of the available clinical data call for re-evaluation of the effect of hyperoxia on the outcome of stroke and on the possibility to use it to extend the narrow therapeutic time window for stroke thrombolysis [ 17].
The discovery of these new properties of classic cytotoxic agents led to the re-evaluation of their effect on vascular cells, rendering thus the endothelium an appealing target for therapeutic intervention, either with chemotherapy alone or with combination of cytotoxics with molecular angiogenesis inhibitors.
Compelling evidence for an over-riding role for glucagon excess in the pathogenesis of diabetes [3,14] and development of non-invasive methods for estimating glucokinase activity in man based on the assumption that glucokinase activity responds to glucose but not to hormones [15,16], calls for a critical re-evaluation of the effect of glucagon on glucokinase translocation and activity.
In human pregnancies, early reports suggested strong teratogenic effects; however, more recent re-evaluation showed that the effects are dose-dependent and could be lessened by controlling lithium intake during pregnancy and within a short period prior to delivery [ 95].
Baskin, J. N. & Williams, E. E. The Lesser Antillean Ameiva (Sauria, Teiidae): Re-evaluation, zoogeography and the effects of predation.
The most urgent task — and one that Mr. Lacoste acknowledged had been neglected — is a re-evaluation of the potential effects of natural disasters on nuclear safety.
Proposals that gammaretroviral vectors encoding suicide genes be employed to selectively kill dividing tumor cells in the nervous system may also require re-evaluation of potential bystander effects on non-dividing cells [47].
The governments of the United States and Canada determined [9] that the water management plan for this ecosystem needed re-evaluation and the potential effects on coastal environments were expected to be important and diverse [10].
From a scientific perspective, the new concerns raised by the recent meta-analyses will undoubtedly stimulate a re-evaluation of the mechanistic effects of glucosamine.
This will require someone, or a group, to monitor and effect periodic re-evaluations.
