Sentence examples for rcc it from inspiring English sources

Although chromophobe RCC has a better prognosis than conventional or papillary RCC, it is a malignant tumor with a tendency to sarcomatoid transformation and metastatic growth in around 10% of the cases [ 1- 4].

Functional studies of mutant pVHL protein associated with differing VHL disease phenotypes (e.g. with differential risks of RCC and phaeochromocytoma) suggest that whereas impairment of the ability to regulate HIF is necessary for predisposition to RCC, it is not sufficient, and impairment of non-HIF-related pVHL functions is also required (Clifford et al. 2001).

Although imaging findings may not reliably discriminate oncocytoma from RCC, it is meaningful for radiologists to understand the wide imaging spectrum of oncocytomas when approaching the differential diagnosis of renal tumours.

In summary, our data, together with a prior study from our institution, comprise one of the largest cohorts of extensively (>90%) necrotic RCCs and suggests that in the setting of a low-grade RCC, it portends a good prognosis (only 2/36 cases showing progression (6%) on follow-up).

As clear cell RCC, it develops in the renal cortex [18], [19].

Further, in RCC, it was shown that an 8-gene classifier set developed from the differentially expressed genes could predict the diagnosis of malignancy with 100% accuracy [14].

In order to clarify the molecular mechanisms involved in the development of high-grade RCCs, it will be necessary to identify the transcriptional target genes of the TEAD-YAP1 complex in RCCs.

In order to verify that this procedure was not overly sensitive to the percentiles chosen to define the rccs, it was repeated by correlating all non-zero voxels in the compared PC image volumes.

Although the expression behavior was not related to the survival outcome of the RCC patients, it can be assumed that these changes indicate fundamental alterations in the fatty metabolism in the RCC carcinogenesis.

Sunitinib has been approved for treating renal cell carcinoma (RCC); however, it inhibits RCC growth through an anti-angiogenesis mechanism rather than by directly targeting RCC cells [38].

However, it may be more practical to consider that a heterogeneous mass in the delayed phase is more likely RCC because it is more common than oncocytoma.