Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
This typical cycle of nadir and peak concentrations is very much in accordance with published data on laboratory rats (plasma samples [38], [39]; faecal samples [40]) and mice (plasma samples [41] [43]; faecal samples [31], [44], [45]).
Similar(59)
Fig. 2 Representative UHPLC MS/MS chromatograms of lesinurad and IS in rat plasma samples.
The rat plasma samples were treated via different methods for qualitative and quantitative analysis, respectively.
To liberate galangin from its glucuronides, some rat plasma samples were treated with β-glucuronidase.
The method selectivity was verified by analyzing blank plasma samples from six rats, blank samples spiked with lesinurad and IS, and rat plasma samples.
Methotrexate and syringic acid (internal standard) were extracted from rat plasma samples by protein precipitation with acetonitrile.
Selectivity was investigated by comparing the chromatograms of six different blank rat plasma samples with the corresponding spiked plasma samples with known concentrations of the analytes.
Figure 1 [ 18 F]FDOPA-PET images of rats and radiochromatograms of rat plasma samples after the administration of [ 18 F]FDOPA.
Testing for specificity involved comparing the chromatograms of six different batches of blank rat plasma samples with that of their corresponding spiked plasma.
Six different blank rat plasma samples were extracted and spiked with the QC samples at three concentrations (10, 1000, and 25,000 ng/mL).
Our results revealed that the oxidized products of galangin (kaempferol and quercetin) were not measurable in the rat plasma samples (Figure 1).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com