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These findings in rats indicate that the corticotropin-releasing factor CRF1 receptor antagonist R278995/CRA0450 is centrally active under standard conditions as it inhibits REM sleep and promotes wakefulness.
The results of the in vivo studies which were performed in Spraque Dawley rats indicate that both the fiber optic and electrochemical sensors monitor pH with very little drift.
Studies on the brains of chirping rats indicate that chirping is accompanied by a surge in chemicals that create a feeling of pleasure.
The mechanisms behind this accumulation are not fully understood, but studies on rats indicate that endocytosis either via the megalin-cubulin complex, or via ligand-specific endocytosis, pinocytosis, organic anion and cation transporters families, and oligopeptide transporters, are involved [5, 8, 10 13].
The detection of unilateral components in mice compared to bilateral components for the same networks in rats indicate that the LFF of left and right cortices are different in mice while being similar in rats.
Our data showing that atorvastatin inhibits JNK phosphorylation/activation in septic rats indicate that the beneficial effect of this drug in improving survival and reducing insulin resistance is mediated by different pathways.
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Evidence from RCS rats indicates that failure of RPE cells to phagocytose outer segments results in reduced lipofuscin levels [ 40].
Evidence that p300 might be important in the intestines has been reported, with mRNA analysis in the rat indicating that p300 is expressed in excess of CBP.
The resulting plots are highly correlated for both mouse and rat, indicating that indeed the two array studies generated highly similar results.
Laboratory research, supported by Pfizer, in which P57 was injected into the brains of rats, indicated that it might act on the hypothalamus, a center of appetite control.
Studies in rats indicated that the abnormal expression of c-Jun transcription factor observed in schizophrenic patients was not related to post-mortem intervals or chronic treatment with antipsychotic medications.
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