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Table 3 presents the adjusted odds ratios of utilization of each imaging modality.
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Fig. 3 Relative utilization of cancer drugs in Mexico, by number of years since launch (index: ratio of utilization y years since launch to utilization 16 19 years since launch).
The ratio of utilization of the two AUG codons was altered to favor AUG2 when the EJC was targeted to AUG1.
In addition, an LNA oligonucleotide targeted to various sites in the 5' leader reduced expression from both AUG codons without affecting the ratio of utilization.
These results indicate that binding of an antisense oligonucleotide in the 5' leader of an mRNA does not necessarily affect the ratio of utilization of two AUG codons, but does have a general inhibitory effect.
To determine whether the ratio of utilization of two AUG codons is altered by binding of an antisense LNA oligonucleotide to various locations in a 5' leader other than that of AUG1, we generated a series of mRNA constructs with isosequential 5' leaders by inserting an LNA-target sequence into different parts of the 5' leader of the (CAA)16 CAT-FLAG mRNA (Figure 5A).
**Utilization ratio = ratio of utilization for experimental group patients to utilization for comparison group.
In addition, severity of illness affects the ratio of utilization of different types of healthcare institution.
The range of the actual to predicted ratio of utilization was 0-1.49 0-1.49pendectomy, 0-3.88 for colectomy, 0-6.68 for hysterectomy, appendectomyor lung lobectomy.
Hospitals are listed on the x axis in increasing order from lowest to greatest observed to predicted ratio of utilization of minimally invasive surgery.
In short, all of the reasons mentioned above may contribute to the results of the model of effect on the ratio of utilization of different types of health care provider.
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