In this study, 11 features (including 8 re-used features and 3 newly-designed features) are rationally utilized to reflect the general contents and spatial arrangements of the secondary structural elements of a given protein sequence.
The two-dimensional sandwich-like Pt/Mn3O4/reduced-graphene-oxide (RGO) nanocomposites are successfully fabricated through a spontaneous and electroless approach, where Mn3O4 is rationally utilized as a green reducing agent in the synthesis of Pt nanoparticles and also a superior metal oxide support for the growth of Pt nanoparticles.
Therefore, nanomaterials need to be designed rationally while utilizing aggregation phenomenon for biomedical applications with their potential stability and toxicity in count.
Hence, biological H2 production from lignocellulosic biomass such as cornstalk can not only help utilize this resource rationally, but also reduce the earth's dependence on fossil fuels.
This new series demonstrates that DFG-out kinase inhibitors can be rationally designed from related inhibitors which utilize an unconventional binding mode.
It is obvious that clinical judgment of a resident or general practitioner may not be similar to that of a specialist who can utilize laboratory investigations more rationally using his superior clinical acumen.
Therefore, the ability to utilize phage display to rationally engineer sophisticated reagents as highly selective inhibitors with defined behavior can serve as a powerful approach to investigate the diversity of structural states of cell-surface receptors and to design new drugs.
In this article, we emphasize methods by which block copolymer self-assembly can be utilized to rationally design and control the shape and dimension of resulting nanostructures and therefore to develop idealized morphologies.
The important feature of this type of approach is to effectively utilize the redox-active functional groups on graphene sheet surface by rationally designing conductive 3D porous structures.
In order to utilize this enzyme, it is necessary to understand the topography of the active site to rationally design compounds that are more potent and selective substrates for Ado kinase.
