With rationally sequence designed, massive long DNA molecules with multiple G-quadruplex units were formed to generate the G-quarduplex/hemin complexes in the presence of hemin, which could enhance the ECL efficiency of luminol-H2O2 system due to its strongly catalytic performance toward the coreactant H2O2.
These ideas may be either loosely related impressions approaching free association or more rationally structured sequences of thought and emotion.
Mengiste has inadvertently created a work that looks into the horror and sees a rationally ordered sequence of events.
We sought to evaluate the activity and tolerance of the rationally designed sequence of paclitaxel topotecan etoposide, a nonplatinum regimen, as induction therapy for limited-stage small-cell lung cancer before combined chemo- and radiotherapy.
Rationally designed sequences afford the ability to tailor biological activity.
The new 49-nucleotide rationally optimized sequence was capable of enhancing the catalytic rate approximately 20000-fold.
The ability to identify essential genes in the absence of experimental data is of added importance, because it allows for a system to rationally select possible drug targets for newly sequenced pathogens.
This work aimed to use molecular dynamics simulations to understand the interactions of rationally obtained peptide sequences from the original sequence of the OmpA gene in Escherichia coli, based on the free energy change (ΔG) during peptide insertion at the water dodecane interface.
Both proteins were targeted for secretion using a YAP3 pre sequence (21 amino acids, cleaved off in the ER) and a rationally designed pro sequence (TA57, 42 amino acids, no glycosylation or disulfides) were cloned behind a TDH3 promoter in a high copy 2 micron plasmid [ 18]. α-amylase was expressed using the same plasmid, promoter, and leader sequences.
The N-terminal domain of KanF and the C-terminal domain of GtfE were fused with rationally designed linker sequences.
