Sentence examples for rationally identified from inspiring English sources

We here describe how synthetic oligosaccharide epitopes for candidate vaccines can be rationally identified prior to preclinical immunogenicity studies.

Interestingly, the ascorbic acid also directed the primary nanocrystals to anisotropic aggregations, and the growth mechanisms were rationally identified by TEM and x-ray diffraction.

In conclusion, the results demonstrated that juice yields and phenolic yields in elderberry juice could be improved with enzyme treatment and that the optimal reaction conditions for obtaining the best juice yield, highest phenolics, and lowest turbidity levels could be rationally identified via statistical factor level optimization.

The central aim of this study was to evaluate if etodolac exposure would alter rationally identified biomarkers in women with resectable breast cancer.

We evaluated the effect of etodolac, an FDA-approved NSAID reported to inhibit cyclooxygenase (COX) enzymes and the retinoid X receptor alpha (RXR), on rationally identified potential biomarkers in breast cancer.

Assay of a limited set of rationally identified genes, evaluated before and after etodolac exposure, found that etodolac is associated with a decrease in cyclin D1 protein level as assayed by immunohistochemistry.

This notion of human motivation deepened during the Enlightenment, whose leading thinkers, despising tradition and religion, sought to replace them with the human capacity to rationally identify individual and collective interests.

To design a pharmacologically active drug for site-specific activity is a challenging task that begins with rationally identifying the targets to which that drug binds.

New techniques are needed to systematically and rationally identify targets and pathways that may be synergistic targets.

This system was designed to target the melanocortin receptors (MCRs), with functional group selection based on a known pharmacophore and guidance from molecular modeling to rationally identify positional and stereochemical isomers likely to be active.

A comparative transcriptome profiling between a riboflavin-producing Bacillus subtilis strain RH33 and the wild-type strain B. subtilis 168 was performed, complemented with metabolite pool and nucleotide sequence analysis, to rationally identify new targets for improving riboflavin production.