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Since in this view the attributes are only rationally distinct from the substance, the "real distinction" between the attributes, that Spinoza states in 1P10Schol, is understood as being only an epistemological claim, as he states in the text—"i.e., one may be conceived without the other" (1P10Schol).
This identity can be understood strictly if the distinction between the attributes and the substance is taken to be only rationally distinct, that is identical in reality, and at the same time taking the distinction between attributes to be only epistemological and not ontological.
Meanwhile, Descartes's view that material or formal reality and objective reality are only rationally distinct might be taken to mean that minds are intrinsically intentional.
Descartes calls the distinction between attributes of the same substance, and between a given attribute and its substance a "rational distinction," (Principles, I, §62, CSM, I, p. 214, AT 30) and so, insofar as Thought and Extension belong to the same substance for Spinoza, they would be, in Descartes' terminology, rationally distinct.[8] Spinoza however, says that they are "really distinct".
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The problem of the relational nature of the contents of true singular thoughts can be made more acute by the following puzzle that exercised Gottlob Frege (1892): how can one rationally hold two distinct singular beliefs that are both about one and the same object?
In a strict rationalist vein, by contrast, what appears before the mind are ideas, rationally formed "clear and distinct ideas" (in René Descartes' ideal).
With regards to the second issue, although early drugs were discovered serendipitously, multi-target compounds are now rationally designed, typically by combining two distinct frameworks into a single chemical entity [38 40], starting from compounds with the desired activity towards the targets of interest.
This is the principle that conflict between distinct moral or practical considerations can be rationally resolved only on the basis of some third principle or consideration that is both more general and more firmly warranted than the two initial competitors.
To do so, we need to rationally divide total D-AAs into two subsets with distinct Raman spectra.
Stoicism teaches that the universe is rational, that it can be explained rationally, and organized rationally.
The identification of adjuvants and immunomodulators, that can promote the selective induction of these distinct populations of T cells, has now made it possible to rationally design safe and effective mucosal vaccines against a range of infectious diseases of man.
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