Sentence examples for rationally developed from inspiring English sources

Rationally developed nanoparticle vaccines are one of the most promising candidates for the future of vaccine development.

The rational use of agents capable of abrogating drug resistance offers other opportunities for systemic chemotherapy that may then give rise to more rationally developed combinations.

It highlights the transition from nonspecific drugs like steroids and azathioprine to highly engineered and rationally developed protein-based therapeutics such as the costimulation blocker belatacept.

A simple and versatile ratiometric fluorescent Fe3+ detecting system, probe 1, was rationally developed based on the Fe3+-mediated deprotection of acetal reaction.

Trastuzumab (Herceptin; F. Hoffmann-La Roche, Basel, Switzerland), an anti-HER2 monoclonal antibody (MAb), was one of the first rationally developed and clinically available targeted agents, setting the precedent for providing specific therapy for HER-dysregulated cancer.

Here, we have rationally developed a multifunctional platform using a self-assembly strategy to incorporate materials with specific functions of chemotherapeutics, hyperthermia, and especially immunotherapy, which can collectively contribute to the effective cancer treatment.

"It's a new way to rationally develop antiviral drugs," says veterinary microbiologist Jürgen Richt at Kansas State University, Manhattan, who was not involved in the study.

However, it is necessary to understand why BCG has failed before we can rationally develop the next generation of vaccines.

In our mission to rationally develop novel effective small molecules against Hsp90, we predicted the potency of our designed compounds by Sybyl surflex Geom X docking method.

In continuation of our goal to rationally develop effective small molecule azomethines against Hsp90, we designed few more compounds belonging to the class of 2,4-dihydroxy benzaldehyde derived imines (1 13) with our validated docking protocol.

The recent identification of several genes with mutations linked to familial forms of PD has provided unprecedented opportunities to discover potential pathogenic mechanisms and to rationally develop more effective therapies [5].