Hence, alternative cis and trans-splicing events generating different and perhaps tissue specific Dumpy isoforms can provide a rationale for the complexity of this long studied Drosophila gene.
The rationale for using only the mucosa was to decrease the complexity of the bladder system, getting closer to the urothelial cell in culture used by the other authors [ 31, 32].
The complexity of the PA calculation is described, and the rationale for developing a flexible, robust run-control process is discussed.
In recent years, numerous DNA sequencing studies have unraveled the complexity of cancer genomes and have provided a molecular rationale for the remarkable heterogeneity that is commonly observed among cancers that share identical pathological features.
Collectively, these findings illustrate the complexity of the regulatory mechanisms within the cluster and provide a rationale for the heterogeneity in diversity levels observed within the HBD– HBBP1 region.
Overall this study underlines the complexity of targeting ERBB signaling for cancer therapy and provides a mechanistic rationale for combination therapy to overcome drug resistance when targeting the ERBB signaling pathway for cancer treatment.
The rationale for use of a particular survey method is often based on its practicality, cost and the complexity of the questions to be answered.
The GPs' different views, regarding the rationale for and practical management of primary prevention of CVD, can be interpreted as a reflection of the complexity of patient counselling in primary prevention in clinical practice.
A common underlying rationale for the choice of a joint organisational form, as opposed to a traditional contracting-out agreement concerns the complexity of the services delivered.
So is the complexity of the job.
