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Among the patients with complete data, we excluded 17 patients who did not pass the rationale test, which were two warm-up choice tasks.
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The high in vitro and in vivo sensitivity of LM1 cells to ALK inhibition supports the rationale testing these compounds for ALK-positive DLBCLs.
Notwithstanding such limitations, the chosen trial simulation could establish the rationale of test accuracy of the Berger-Exner test by providing first insights as to which aspects, present in randomised control trials, may affect its utility.
With this rationale, the test arm with the highest observed response rate was to be identified as the most efficacious test arm.
Recent data indicate that calcineurin inhibitors activate the thiazide-sensitive sodium chloride cotransporter, providing further rationale to test thiazides in this population.
By showing that ATR inhibition mimicked the effects of WDR5 suppression, these data provide rationale to test ATR and WDR5 inhibitors for activity in this disease.
The rationale to test the former is that high-glucose culture conditions as well as in vivo hyperglycemia have been recognized as critical factors for the differentiation of adult stem cells into insulin-producing cells [32], [33].
Phylogenetic relationships among genotypes showed a reticulate network pattern providing a rationale to test for recombination.
This was the rationale to test 240 mg as a starting dose in subsequent trials.
First, the retrospective design precluded a complete understanding of the rationale for test ordering.
They help individuals to recall their initial motivation and rationale to test.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com