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Rationale: Summary scores imply an implicit weighting of the criteria that is not evidence-based but arbitrary.
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A SOR document typically contains a collection of 'clinical algorithms' to be consulted in appropriate situations together with a succinct summary, rationale, and evidence for the Standards, Options and criteria for Recommendations covered by the algorithms.
We do not expect authors to discuss every single event or type of event; rather we would still expect them to draw the reader's attention to the most important events (supported by a clearly stated rationale) within this summary data.
The latter is not expected to be problematic, as while the similarity between tissues can be small, it is unlikely to be 0. The rationale for this summary statistics is that if there is no detectable effect of an LTR on gene expression pattern in either of the two tissues, the coregulation of LTR-associated genes will not differ significantly from the coregulation of remaining genes in the genome.
The third rationale for forming other summary measures was to use underlying biologic mechanisms that were suggested by others.
The implementation researchers provided two additional perspectives with one being intimately familiar with the data, having conducted the interviews and reviewed and analyzed the transcripts (LJD) and the other regularly questioning assumptions and conclusions to help ensure strong rationale for coding and summary statements (JCL).
At the time of the ADNFS survey (1990), three episodes of at least moderate activity of 20 min duration per week were recommended for maintaining/improving cardio-respiratory fitness and provide the rationale for producing a summary of current activity based on the number of occasions of moderate to vigorous activity of at least 20 min duration for each main activity type [ 14].
Better still would be to follow Warsh's recommendation to promptly release a three-part policy statement made up of the decision, a summary of its rationale, and individual MPC votes.
A written summary of the rationale was given to the patients.
The toolkit starts with an executive summary including the rationale for diabetes prevention.
All clinical recommendations made by MATE are presented to the user together with a summary of the rationale in the form of arguments and supporting evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com