Sentence examples for rationale of testing from inspiring English sources

The other rationale of testing such a wide range of the ICF codes is that elderly persons hold problems that cover multiple disciplines.

Together, these data support the rationale of testing netrin-1 interference based therapy in early clinical trials in combination with conventional chemotherapies.

These results suggested that HDACi and doxorubicin combinations could be useful for treating patients who recur on existing therapies and provide a rationale of testing this combination in clinics.

The presence of DTCs after chemotherapy clearly indicates a rationale for testing of alternative (secondary) treatment approaches.

Closer examination of the pathways identified will be necessary to provide a rationale for testing inhibition of specific targets in combination with SINE compounds to enhance the activity of SINE compound mono-therapy.

Notwithstanding such limitations, the chosen trial simulation could establish the rationale of test accuracy of the Berger-Exner test by providing first insights as to which aspects, present in randomised control trials, may affect its utility.

These findings provide the rationale for testing blockers of collagen-binding sites, such as revacept and galectin-3 inhibitors in the prevention of colon cancer metastasis in animal models.

The findings of our study provide a rationale for testing the therapeutic effects of pazopanib in patients with unresectable HCC.

These results combined with previous reports indicating that the inhibition of STAT3 activation can enhance the radiosensitivity of certain tumor cell lines 41, 42 provided the rationale for testing the effects of WP1066 on NSC11 cells grown in coculture with astrocytes and in vivo as orthotopic xenografts.

As several natural agent TRAIL agonists are currently under clinical development, these results in human myeloid leukemia cell lines and primary PBMCs provide a rationale for testing the combination of Med and TRAIL agonists in management of myeloid leukemia.

We believe that the clinical case reports of abscopal effects, and the preclinical models summarized above provide a strong rationale for testing the combination of radiotherapy with immune checkpoint inhibitors, specifically PD-1/PD-L1 inhibition, in clinical trials for humans.