Sentence examples for rationale of ongoing from inspiring English sources

We will also present the design and rationale of ongoing trials looking into the use of third-generation aromatase inhibitors in the adjuvant setting and review data regarding their possible role in premenopausal women.

However, these observations strengthen the rationale of the ongoing study randomizing treatment maintenance vs interruption after 6 cycles which is currently ongoing within the French Sarcoma Group (NCT01303094).

These data support the rationale of an ongoing phase III study exploring the potential benefit of tifacogin in severe CAP.

The present preclinical study permitted us to define the most effective three-drug sequence, providing the basis for the rationale of an ongoing phase I/II breast cancer clinical protocol in which the oral formulations of Dox and 5-FU are used to reduce toxicity and increase safety of treatment schemes.

Our findings therefore add support to the rationale for ongoing clinical trials in which higher doses of rifampin for treatment of tuberculosis are being evaluated.

These findings provide a further rationale for ongoing clinical studies aimed at the use of drugs that inhibit apoptosis [ 45] and therapeutic removal of inflammatory mediators by extracorporeal techniques [ 46].

The knowledge accumulated during the past decade has provided a better rationale for ongoing dengue drug discovery.

The limited single-agent activity of rapamycin analogs in several GBM trials [ 25, 26] provides a rationale for ongoing clinical trials with dual PI3K/mTOR inhibitors in GBM.

Nevertheless, consistent changes in these vascular parameters are encouraging and support the rationale for ongoing long-term cardiovascular outcome trials.

However, the mechanistic rationale for this dichotomy are the subject of ongoing debate.

The review found that "the DEA did not consistently follow its policy or process and failed to document the rationale for its decisions" to reward employees who committed "significant misconduct" or were the subject of ongoing investigations.