Sentence examples for rationale of new from inspiring English sources

Signifying the coming of age of tumour-specific targets and agents was the recurring theme, to urgently develop and validate biomarker assays as surrogate endpoints; both for showing that targeted agents act as expected and for providing proof of concept in the scientific rationale of new agents.

Results lay a foundation for a rationale development of new leads from Nijatryp library.

We suggest that the high genetic polymorphism of ERG11 must be considered in the rationale design of new azole compounds targeting lanosterol 14α-demethylase.

The understanding of the functional interplays between receptor is of major importance for the rationale design of new therapeutics in cancer.

Altogether, this work highlights the potential of miRNA functional studies to decipher cell signalling pathways or major regulatory hubs involved in cell survival to finally propose the rationale design of new strategies on the basis of pharmacological combinations.

Section 2 is devoted to the data model of side-looking airborne or spaceborne radar, while the detailed rationale of the new method, including the SR model and the new DA-GIP algorithm, are presented in Section 3. In Section 4, simulations are given to show the effectiveness of the proposed DA-SDS-SRSTAP method.

We often see the police as the solution to crime problems and so it goes for the rationale of this new initiative.

On March 2nd the prime minister sent a circular to the head of each of France's regional departments to explain the rationale of the new law.

In this short communication, we explain the rationale of a new type of lung recruitment maneuver the postural recruitment (P-RM).

Purpose / Objective It is believed that an evaluation would strengthen the rationale of the new Programme.

The present paper reports on the design rationale of this new short stem prosthesis and the methodological design of the study.