Sentence examples similar to rationale of loss from inspiring English sources
ABO promoter methylation in UC has been described although the biological rationale for loss of expression of the ABO blood group gene in cancer is unclear.
The evidence that DMR1 CpG 5 is one of the target sites responsible for the binding of methyl-sensitive Ctcf [ 23], gives an intriguing rationale to the loss of binding of the complex that we detected in these regions upon overexpression of PARG.
Thus, structural perturbations of the Fc provide a rationale for the loss of function.
Following this rationale, the loss of ECM during degenerative joint diseases, such as in osteoarthritis, and the decrease in the osmolarity of the chondrocyte microenvironment could contribute to the decreased levels of SOX9 mRNA observed in chondrocytes within osteoarthritic cartilage (1, 14, 33).
We compared these findings to synthetic lethality and pharmacological screening results in isogenic CDH1−/− MCF10A mammary epithelial cells with and without CDH1 expression and current knowledge of E-cadherin/catenin EGFR cross-talk, and suggE-cadherin/catenin EGFRs how loss of E-cadherin function activandsuggest mTOR, EGFR, or FAK signaling.
Many have voiced concern that PITC policies may be accompanied by reduced levels of counseling and high levels of loss to follow up, both of which weaken the rationale for scaled up testing [ 11, 12, 73].
Recently, a new rationale distinct from the one that understands human death in terms of loss of organismic functioning mediated by the brain has been advanced in support of the whole-brain standard (PCB 2008, ch. 4).
The local and contextual processes of how loss and the risk of loss are interpreted provide insights, not only on the sequencing of seeking treatment, but also on caregivers' rationales for preferences for private and public care.
Function of loss assessors.
