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(iii) Use machine-learning techniques for analyzing molecular dynamics trajectories: we will discuss the rationale of examining both full-atom and coarse-grained molecular dynamics trajectories using machine-learning techniques, what additional knowledge can be extracted, and how next-generation QSAR models could benefit of such technology.
The rationale of examining our datasets for an interferon signature was based on our previous observation in prostate cancer showing that interferon γ-responsive genes are up-regulated in African-American tumors [12].
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The results of this study provide a rationale for examining the use of IDR-peptides as potential therapeutic candidates for chronic inflammatory diseases such as inflammatory arthritis.
The rationale for examining attitudes of livestock farmers in part flows from calls to produce DECs on land not needed, or unsuitable, for food crops.
Kang et al. recently demonstrated that early innate immune events were detrimental to the development of emphysema in smoke-exposed mice [13], providing further rationale for examining the impact of acute cigarette smoke exposure to H1N1 influenza antiviral responses.
Nevertheless, our data showing that miR132 markedly affects MeCP2 expression in vivo, provide a strong rationale for examining whether dysregulation of miR132 could be contributing to Rett Syndrome and other MeCP2-related disorders.
These potentially negative consequences provide the rationale for examining the ethics of peace-building interventions.
The rationale for examining alternate uses of birth control was to examine specificity for OCs, as it is plausible that this measure is a marker of sexual activity, which itself has demonstrated some inconsistent association with prostate cancer.
Data from studies that administered a chelator to animals with experimental autoimmune encephalomyelitis, a model of MS, support the rationale for examining this treatment approach in MS. Preliminary clinical studies have been performed in MS patients using deferoxamine.
The rationale for examining antibody responses against many of the autoantigens was their known associations with autoimmune diseases such as T1D, SLE and myositis.
The rationale for examining first productions was to calculate segmental accuracy of the productions of each NW the first time they were produced.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com