If the underlying rationale is plausible, in addition to the procedure or concept being accepted by many clinicians, then it is likely that it will be considered relatively "acceptable".
This article describes the rationale supporting the trial in addition to reviewing the study design, coordination, and governance.
If specific BRAF inhibition is applied, there is a rationale to give it in addition to broad acting drugs.
The work presented in this rationale has established that hexafluoroacetone, in addition to its intrinsic qualities, such as the production of light-weight derivatives (no racemization) and great resistance to the drastic operating conditions, has indeed facilitated simple and fast derivatization that appears to be suitable for in situ analysis in space.
This paper overviews the design and rationale of these two studies, in addition to a description of approaches for biomarker discovery focused on existing cohort studies that are accessible to the Consortium.
The rationale for applying self-report in addition to the objective BAC level, was that many of the patients arrived in the hospital many hours after the injury occurred, and in these cases the injury could be alcohol related but not detected in the blood alcohol determination/analysis.
We provide an outline of the rationale for CINODs and their activity, in addition to an overview of the pre-clinical and clinical profile of the most advanced CINOD, naproxcinod.
In addition to this strong rationale [ 1], there is one additional indication for rapamycin, regardless of progerin clearance, namely suppression of geroconversion (conversion from quiescence to senescence) by rapamycin [ 2, 17- 19].
In addition to functional rationales behind ventricular lead positions, practical aspects should be taken into account when choosing the optimal site of pacing for rate control in the individual patient.
