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27 A key problem encountered with anti-infectives is that the rationale for usage and proposed course of treatment is often poorly documented.
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A negative answer is suggested by William's rationale for his usage.
The elevated transport of the G3.5 PAMAM dendrimers through isolated tissue gives rationale for dendrimer usage in oral drug delivery.
This highlights the continuous interest in laboratory screening of medicinal plants, not only to determine the scientific rationale for their usage, but also to discover new active principles.
Objective: This study examined the usage patterns of dietary supplements during pregnancy, providing information about type of supplements used, prevalence of use, and rationale for use.
In this study, our clear demonstration that thiostrepton could synergize with oxaliplatin, a widely used CRC chemotherapeutic agent, in killing CRSCs, strengthens the rationale for its clinical usage in CRC treatment.
Moreover, the clinical reality is that these patients are prone to seizures due to their cocaine usage, which provides a compelling rationale for the urgent prophylactic use of benzodiazepines in these situations.
This suggests a biological rationale for the differences in exon usage observed in this study.
Also, it is important to note that the mutations impacting K36 methylation (K36M and G34 mutants) are only in H3.3, with little rationale for this selection based on codon usage.
Based on the findings, we conclude that further research is needed to develop methodology and tool support for design rationale capture and usage.
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