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These results provide a rationale for testing the combination of Yondelis and DDP in the clinic.
These studies served as the preclinical rationale for testing the FAK inhibitor, Defactinib VS-60633) in KRAS mutant NSCLC.
Our data provide a compelling rationale for testing the combination of anti-cytokine and epitope specific immunotherapy in human autoimmune disease.
These findings underline the importance of simultaneously targeting Akt and mTOR to achieve significant down-regulation of the PI3K pathway and support the rationale for testing the perifosine and CCI-779 combination in the human PDGF-subgroup of GBM.
This finding provides a powerful rationale for testing the protective activity of these relatively conserved viral components in humans.
The findings of our study provide a rationale for testing the therapeutic effects of pazopanib in patients with unresectable HCC.
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The rationale for testing this earlier inoculation time point is that the vaccinia response usually peaks around day 7 after immunization and it would presumably have better control of tumor growth, as opposed to day 11 days after Vac-LMP2A immunization when the Vaccinia virus response is starting to decline.
Should these studies prove encouraging, there would be a rationale for testing these inhibitors in cases of ductal carcinoma of the breast in clinical trials.
Most importantly, the Michigan law was struck down as unconstitutional, with the judge ruling that the rationale for testing people on welfare "could be used for testing the parents of all children who received Medicaid, State Emergency Relief, educational grants or loans, public education or any other benefit from that state".
Interaction models: the fact that the origin of islet autoantibodies detected in newborns most probably is of maternal origin was the rationale for testing for interaction between the effect of maternal type 1 diabetes and the presence of islet autoantibodies on type 1 diabetes risk.
These data represent a strong rationale for testing PLD in the first line treatment of ovarian cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com