Sentence examples for rationale for selectivity from inspiring English sources

In the general frame of a project aiming at screening candidate drugs against several different matrix metalloproteinases (MMP) to find a rationale for selectivity, the catalytic domain of MMP-12 (metalloelastase) has been expressed in E. coli strain BL21D3 and its production optimized to about 30 mg/dm30

This model provides a rationale for selectivity in IEX of peptides and addresses a number of issues that have appeared in the literature: Peptides with the same net charge can be separated by IEX: While factors such as charge-to-mass ratio surely play a role, the orientation effect explains why sequence is important as well.

Does the rationale for selection vary over time and contexts?

This selectivity engineered PTC reaction has been investigated from mechanistic viewpoint and the rationale of selectivity is delineated.

This alteration to a key point of interaction with the activators, as evident in the crystal structure, provides a structural rationale for the measured selectivity.

On the basis of the structure of holoPAD2, this loop is mobile, however, and as such may not provide the complete mechanistic rationale for the high selectivity.

In particular, they provide a rationale for the experimentally observed very high selectivity of H-Fer for the skeletal isomerization of n- butenes, as well as its rapid deactivation.

In addition, the modeling rationale was based on superimposing the structures of Aurora-A kinase and CDK2 which revealed enough differences leading to a path for selectivity improvement.

Although Rosenthal Wine Merchant's reputation for selectivity flows from its French portfolio, its smaller Italian collection is equally discriminating.

The structure thus offers a simple rationale for the altered distribution of ions in the selectivity filter of the toxin-bound channel.

These data provided the rationale for the need to clinically evaluate MSC as selective modulator of the antitumour activity and selectivity of anticancer drugs.