These metabolic effects provide a rationale for further studies during periods of hypoxia and ischemia.
These findings highlight a rationale for further development of CDK2 inhibitors to treat human breast cancer.
A range of perioperative therapies are introduced and the rationale for further clinical investigation outlined.
In pitting the deserving poor against the undeserving, we take the outcome of a brutal system and use it as a rationale for further brutalisation.
These results provide a strong rationale for further exploring the potential of elesclomol in AML, a disease with high medical need and limited options for patients".
For example, limits on the deductibility of executive pay in the early 1990s provided a rationale for further explosion in equity-based compensation.
This suggests a complex network of interactions between S. aureus and the human extracellular proteome, providing the rationale for further investigations at the host-pathogen interface.
Phenformin treatment significantly diminished PDAC tumor progression and prolonged tumor doubling time, which provides rationale for further clinical evaluation of phenformin as a therapeutic agent in pancreatic cancer.
Taken together, the results reported here provide a rationale for further development of compound 3 as a lead in the design of dimeric Smac mimetics for cancer treatment.
Although this issue was beyond the scope of the original study, the volume of data and recurrence of this issue provided a strong rationale for further exploration.
These results provide a rationale for further investigations aimed to exploit in a similar fashion to cancer targeted therapies for a "precision medicine" approach to IPF.
