What was the rationale behind, for example, changing the shading on the fruit?
Moreover, if the IATA is based on mechanistic rationale, derived, for example, from knowledge described as an AOP, then the value of the method will be related to its (mechanistic) relevance to key events and the reliability (reproducibility) of the data it generates.
Incorporating a clinician's rationale for transfusion (for example, acute bleeding) or the role of symptoms (chest pain or dyspnea) would add further detail that may further explain practice variation not reflected in the admission or pre-transfusion hemoglobin.
The Toolkit provides a description of the measure, detailed protocols associated with the measure, and other related information: for example, rationale for selection, equipment and training required, and references.
Although the rationale for such combinations, for example chemo-immune therapy, is mostly empiric chemo-immune therapy still is the most promising approach.
They also encouraged thorough communication with patients about their plan of care and the rationale behind the plan, for example, why certain medications are being prescribed or the reasons for fasting before a medical test.
It may also be appropriate to include here the objectives of the trial (see item 2b .The rationale may be explanatory (for example, to assess the possible influence of a drug on renal function) or pragmatic (for example, to guide practice by comparing the benefits and harms of two treatments).
Readers are referred to the CONSORT PRO Extension for further information on the rationale for each item, examples of reporting and elaboration of the existing CONSORT 2010 statement in relation to PROs [ 11].
Of course many efforts are directed at the creation of more rationale, and user-friendly, databases, for example of biological interactions.
For example, the rationale for encouraging innovation was applied to the energy criterion in beverages.
