The rationale behind escalating therapy is that treatment starts with safe drugs and only moves on to more aggressive ones if the ongoing treatment fails.
The rationale for HDCT is that escalating doses of HDCT may increase survival by capturing putatively remnant malignant cells and thus overcome cell resistance to standard chemotherapy [7].
The rationale for HDCT is that escalating doses of HDCT may increase survival by capturing putatively remnant malignant cells.
Even if non-pharmacological management strategies fail to demonstrate the clinical benefits, there could be a rationale for adopting them if they address the escalating costs of AD.
RICHMOND — The surprise battle between Virginia Gov. Terry McAuliffe (D) and the gun-control organization founded by former New York mayor Michael Bloomberg escalated Tuesday to include a full-page newspaper ad skewering the governor's rationale for a gun deal with Republicans.
Together, these findings may provide a rationale for initiating treatment with combined quetiapine XR and lithium in patients with severe acute manic symptoms, rather than escalating the dose of monotherapy up to the highest dose approved, and hence also for subsequent use of this combination as maintenance treatment to prevent recurrence.
The Clintonites have already begun using the L-word, and that will surely continue and escalate; indeed, the issue of legitimacy can be (and likely will be) used as a rationale for Hillary's remaining in the race, despite the slim odds of her succeeding.
Fracasso PM, H Burris 3rd, MA Arquette, R Govindan, F Gao, LP Wright, SA Goodner, FA Greco, SF Jones, N Willcut, C Chodkiewicz, A Pathak, GM Springett, GR Simon, DM Sullivan, R Marcelpoil, SD Mayfield, D Mauro, CR Garrett (2007) A phase 1 escalating single-dose and weekly fixed-dose study of cetuximab: pharmacokinetic and pharmacodynamic rationale for dosing.
Hence another rationale for nationalism.
Mr. Rosenstein had been under escalating pressure from Democrats, and even some Republicans, to appoint a special counsel after he wrote a memo that the White House initially cited as the rationale for Mr. Comey's dismissal.
