Sentence examples for rationale for development from inspiring English sources

The involvement of FGF/FGFRs in the pathology of many cancer types provides a strong rationale for development of effective agents for these targets and a large effort to develop FGFR inhibitors as anticancer treatments is underway (Brooks et al., 2012, Dieci et al., 2013).

If extreme poverty declines significantly over the next 20 years, as economic growth continues in the south, the rationale for development co-operation under a poverty eradication paradigm might diminish.

This paper reports on the rationale for development, design, and evaluation of a module of study for staff who care for children with complex needs and their families.

Hence inhibiting the eIF4F checkpoint suppresses tumor growth through multiple mechanisms and provides a rationale for development of broad-acting therapeutics.

These data indicate that Plasmodium SPP is a potential therapeutic target for malaria, and provide rationale for development of selective Plasmodium SPP inhibitors, perhaps based on the LY411,575 scaffold as novel treatments for malaria.

The rationale for development of the isotope-coded NEM approach was to allow future extension to measurement in parallel of both RSNO and SS protein modifications.

Thus, careful evaluation of both the mechanistic and functional consequences between RIDD activation versus XBP1/HAC1 splicing will provide a greater understanding of how ER stress affects cell physiology and also provide rationales for development of drugs and more effective treatment strategies for ER stress-related diseases.

Barnett describes a threefold rationale for the development and growth of settlements: First, a general distrust that government-sponsored institutions could care for the poor.

The present treatment offers a new and plausible rationale for the development of abnormal grain growth from uniform grain size distributions containing unstable particles.

The rationale for the development of MMA PBMA is much the same as for the development of the HsW model – to eliminate artificial constraints that entrench allocative inefficiency.

There should be clear and concise rationale for the development of economic models and the assumptions used to develop models need to be provided.