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EPR answers "yes", but it does not provide a clear rationale for that conclusion.
The authors of one meta-analysis reported that half of studies reviewed did not include representative samples but did not provide a rationale for this conclusion.
Yet it is likely that Vgll1-TEAD comight might not have interface 3. The rationale for this conclusion comes from the biochemical analysis of YAP/Vgll1 and TEAD interaction., Vgll1 loses its affinity with TEAD when mutations are made in the crucial interface 2 residues.
The rationale for such conclusions is documented as the evidence is combined within and across evidence streams, and the conclusions are clearly stated as to which outcomes are incorporated into each conclusion.
The evaluation will include a synopsis that discusses the rationale for the conclusions.
The rationale for reaching this conclusion was that in the one published study reporting an association (10), the number of subjects was small and the risk of developing this complication in a comparable population was unknown.
There could be multiple dissents or concurring opinions from the justices, each with their own rationale for reaching the conclusions they did.
The discussion and plots, while intricate, describe the rationale for the authors' conclusions.
The rationale for this decision?
The rationale for this decision is multifold.
In conclusion, the rationale for performing WE-MDCT in diverticular disease couples an accurate presurgical visualisation with the possibility to obviate OC or complement a limited endoscopic exploration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com