Sentence examples for rationale existed from inspiring English sources

Whatever rationale existed then in flush times -- perhaps to keep Bank of America or JPMorgan Chase from getting the deal -- has receded in light of Citi's troubled present: tens of billions in losses, tens of thousands of layoffs and a federal rescue that included $45 billion in capital infusions from the Troubled Asset Relief Program, or TARP.

On this basis, a strong rationale existed for the use of bevacizumab, an anti-VEGF monoclonal antibody, for treatment of rMGs (recurrent malignant gliomas).

Sometimes, where no rationale exists, golden therapeutic opportunities emerge.

A biologic rationale exists for the association between metabolic syndrome (MetS) and prostate cancer (PCa).

Although a similar rationale exists for the regeneration of articular cartilage with bioactive factors, advancement in this area has not been as substantial.

However, a clear rationale exists for providing long-term, controlled release of vaginal microbicides in order to afford continuous protection against heterosexually transmitted HIV infection and to improve user compliance.

Not unlike in estrogen receptor-positive breast cancer, mechanisms of resistance are being investigated and rationale exists for thoughtful, well-designed combination regimens such as AR antagonism with CDK4/6 pathway inhibitors or PI3K inhibitors.

Moreover, a compelling mechanistic rationale exists for each gene identified.

Therefore, a rationale exists to use BH3 mimetics to circumvent apoptosis resistance in these cancers.

An underlying biologic rationale exists to support an etiologic role for physical activity in endometrial carcinogenesis.

Hence, a simple physiologic rationale exists for using carbon dioxide monitoring to obtain information about cellular metabolism and global perfusion.