Exact(5)
Understanding the gut microbiome in healthy humans is a foundation for discovering its influence in various important gastrointestinal and nutritional diseases (eg, inflammatory bowel disease, diabetes, and obesity), and for rational translation to human health gains.
This will lead to a better, faster, and more rational translation of this promising combination therapy to the clinic.
The rational translation of SmoC1_cn126 contig contains a three repeats of the motif "XXXGXXTCDKCAQTGVCTCGKN", which aligns with similar cysteine-rich motifs in proteins with epidermal growth factor repeats.
This has also provided the building blocks for rational translation of findings in animal models, for example, pharmacodynamic/pharmacokinetic measures of the reduction of neuro-excitability and pain behavior to reduction of clinical pain.
Early information on tumour and normal tissue pharmacology of new agents, as well as response of tumours to therapy with such agents will aid the rapid and rational translation of ideas from the laboratory to the clinic.
Similar(55)
A rational clinical translation of these results suggests standardized utilization of TAMs as prognostic markers in the scope of pathological evaluation of resected specimens from patients suffering from hilar cholangiocarcinoma.
The rational examination and translation of proteomics data in the context of past clinical trials and the design of future clinical trials must occur before we can march forward into the future of personalized medicine.
Our integrin specific ligand functionalized 3D organoids mimic a lymphoid neoplasm-like heterogeneous microenvironment that could, in the long term, change the understanding of the initiation and progression of hematological tumors, allow primary biospecimen analysis, provide prognostic values, and importantly, allow a faster and more rational screening and translation of therapeutic regimens.
Thus, although polymeric materials offer great potential for new vaccines, the intrinsic immune characteristics can hinder rational vaccine design and translation because the role of the carrier itself may alter how other vaccine components or signals (e.g., antigens, adjuvants) are processed.
But to be effective in the public discourse of a secular state, its translation into parallel rational propositions which nonetheless share a common ethical end-point is optimal, although not essential.
Failing to find in non-Western modes of thought precise translations of comparable rational expressions in their own languages, anthropologists hastened to conclude that the problem must lie with the non-Western modes of thought which appear to lack ways of accommodating rational expressions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com