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These data suggested that it is rational to combine rapamycin with bortezomib for targeted HCC therapy.
It would therefore appear rational to combine antibiotic with a substance that inactivates both bacteria and endotoxins [ 10, 11].
Given that AVP decreases systemic oxygen delivery index (DO2I), it seems rational to combine AVP with an inotropic agent that is able to reverse the decrease in CI and DO2I.
As TACE is the most widely used primary treatment of HCC before LTx and sorafenib is the only proven effective systemic treatment for advanced HCC there is a strong rational to combine both treatment modalities.
Second, the up-regulation of miR-21 was found in both tumour tissues and non-tumour tissues such as plasma and serum; however, in the absence of a proven correlation between these two sources of tissues, it is not rational to combine their results together without any explanation or discussion [ 62].
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Furthermore, based on our results, PIK3CA targeting might be a rational approach to combine with anti-inflammatory cancer therapy.
Our approach to rational design was to combine the properties of a pH-independent peptide, MelP5, which forms large pores allowing passage of macromolecules, with the properties of two pH-dependent membrane-active peptides, pHlip and GALA.
While us "intellectual dumbasses" are able to combine healthy, rational skepticism with a residual faith in mainstream media coverage – that is, to retain the ability to distinguish critically between inevitable ideological bias in editorial line and Illuminati-run mind-control programmes – the conspiracy theorist sees through reality's alluringly deceptive naturalness, its fake facade.
While we "intellectual dumbasses" are able to combine healthy, rational skepticism with a residual faith in mainstream media coverage that is, to retain the ability to distinguish critically between inevitable ideological bias in editorial line and Illuminati-run mind-control programs the conspiracy theorist sees through reality's alluringly deceptive naturalness, its fake façade.
He meant that it needed to combine the more rational, juridical, organisation-minded "Latin" temperament with the intuitive, mystical and contemplative spirit found in the east.
Participatory and dialogical processes are thus needed in risk communication to combine technical expertise, rational decision making, and public values and preferences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com