Exact(4)
Frequent consultations were planned to encourage patients in the following nutritional and rational regimen recommendations.
A rational regimen of marbofloxacin against H. parasuis was determined.
A more rational regimen was recommended according to Monte Carlo simulation results.
A dose of 20 μg once daily administered before breakfast has been established as the most rational regimen of treatment with lixisenatide (Lyxumia).
Similar(56)
This information could be used to design a rational dosage regimen for additional isradipine clinical trials in the treatment of stimulant dependence and related neurovascular disorders.
A simple and stable feeding solution was formulated and a rational feeding regimen designed to yield, depending on the rHA baculovirus used, between 2- and 3-fold enhancements in volumetric rHA production with increased specific productivity compared to the batch culture.
In summary, while the finding that excision repair is controlled by the circadian clock has provided the opportunity for a rational chronochemotherapy regimen, other factors will have to be incorporated into the overall approach in a clinical setting.
A large proportion of current studies do not report key information necessary to devise a rational dosing regimen for patients with acute renal failure receiving continuous renal replacement therapy.
Cimicoxib is an efficacious anti-inflammatory and analgesic drug and thanks to a PK/PD approach, a rational dosage regimen of 2 mg/kg was selected for confirmatory clinical trials allowing in fine the claim that cimicoxib at a daily dose of 2 mg/kg is not inferior to two well-established comparators, namely carprofen and firocoxib.
A better understanding of the pharmacokinetics and bioavailability of phytopharmaceuticals can also help in designing rational dosage regimens.
Biomarker-based studies enable the clinical testing of rational combinatorial regimens of investigational agents using an evidence-based and hypothesis-driven approach.
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