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The other is that on any kind of rational pan-European basis, we should be seeing austerity in the periphery at least partly offset by stimulus in the core.
In a rational world, the way things have panned out would add a lot of credibility.
To address this, new strategies for targeting EGFR in HNSCC are being evaluated clinically including the use of pan-HER inhibitors and rational drug combinations that target several signalling pathways simultaneously (Agulnik, 2012).
The present study introduced the concept 'clamp flex' for the rational design of targeted-inhibitor to overcome the K103N pan-class resistance mutation.
However, since individual mutations do not tend to confer pan-antagonist resistance, the development of real-time strategies to monitor for AR mutation emergence could guide rational sequencing of AR pathway inhibitors.
"It's rational.
The idea is rational.
This was only rational.
"He was completely rational.
So far, so rational.
Read The Rational Optimist.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com