Sentence examples for rational discovery from inspiring English sources

Despite the tremendous therapeutic potential of multi-target drugs, their rational discovery and their development still represent a formidable challenge.

In 2006 Rational Discovery, a cheminformatics service company (since closed down), released RDKit [11] under the BSD License.

The novel synthesis technique and revealed electronic coupling mechanism described herein opens the door for the rational discovery of other bimetallic nanocatalysts with positive synergy.

While the CDK has its origins in academia, both OpenBabel and the RDKit originated in companies (OpenEye and Rational Discovery, respectively) and have subsequently been developed by the community under Open Source licenses.

Molecular modeling studies led to the rational discovery of N1-arylsulfonyl-1,3-dihydro-2H-benzimidazol-2-one as a novel template for the design of new non-nucleoside reverse transcriptase inhibitors (NNRTIs) that are active against wild-type and mutant strains of HIV-1.

Statistical and systems biology methodologies have been proposed for the rational discovery of combinatorial therapies [ 2].

Rational drug discovery approaches have made only limited advances in the discovery of a safe macrofilaricide against the Onchocerca worm.

Rational drug discovery approaches have made only limited advances in the discovery of a safe macrofilaricide against the Onchocerca worm [11].

Much has happened in the process of rational drug discovery in the last decades.

This increases the success rate of the potential drug targets in the rational drug discovery process.

Determining protein small molecule binding affinity is a key component of present-day rational drug discovery.