Sentence examples for rational alterations from inspiring English sources
Insights into the genes and enzymes that govern both the assembly-line production of the conglobatin polyketide and its dimerization are essential to allow rational alterations to be made to the conglobatin structure.
Despite these, previous researchers have been immensely successful at rational alteration of the pathway to produce new analogues of the intermediate 6-dEB (21 – 21).
Rational impressions are those alterations of the commanding faculty whose content can be exhibited in language.
It has not yet been associated with alteration of rational decision-making and has not been shown to increase risk-taking behaviour[ 5].
Targeting these genetic alterations is a rational strategy as cells harboring driver mutations may have a survival advantage [ 7, 8].
Similarly, therapies will be specifically directed at such functional genetic or biochemical alterations, thereby permitting more rational therapy of specific cellular abnormalities in infected patients.
According to Figure 1, the most rational therapy to correct the hemodynamic alterations should be addressed to the correction of the pathogenetic mechanisms; that is, heart contractility/rate, vascular tone or intravascular volume.
Motivation: Recognition models for protein-DNA interactions, which allow the prediction of specificity for a DNA-binding domain based only on its sequence or the alteration of specificity through rational design, have long been a goal of computational biology.
Comparative analysis of the secretomes between RE-10 and wild type (WT) provided more insights into the cellulase system of P. oxalicum and alterations caused by the strain rational engineering.
Reversing these functional alterations in NAc could represent a rational target for the treatment of some reward-related behaviors, including drug addiction.
In summary, modern pharmacopeia facilitates a rational therapeutic approach aiming at reversal of the alterations that account for progressive deterioration of glucose homeostasis, enabling, at least in theory, maintenance of long-term glycemic control.
