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When only direct control costs were considered in the ratio, ROI was slightly negative (1 -0.9).
Ratio ROI mean value/ ICV * age * IQ estimate), df degree of freedom, p.adj (FDR) adjusted p-value, with false discovery rate corrected.
BBB: Blood brain barrier; DMEM: Dulbecco's modified Eagle's medium; FBS: Fetal bovine serum; i.v.: intravenous; MSE: Multislice spin-echo; T2WI: T2-weighted image; Gd-DTPA: Gadopentetate dimeglumine; CE-MRI: Contrast-enhanced MRI; T1WI: T1-weighted image; H/E: Hematoxylin/eosin; SER: Sensitizing enhancement ratio; ROI: Region of interest.
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To calculate the tumor-to-normal tissue uptake (T/N) ratio and the tumor-to-blood uptake (T/B) ratio, ROIs were set on the normal brain parenchyma (usually contralateral normal cerebral tissue excluding ventricles) and the vertical portion of the superior sagittal sinus with the aid of PET/CT fusion images.
The calculation of Relative NF- κB activity was based on ratio of ROI value of treatment group and ROI value of control group to be normalized by cell viability of treatment group [ 19]. 2 × 10 cells were seeded in 10 cm diameter dishes and incubated for 24 h.
We calculated copy number as 2× the ratio of ROI concentration versus reference concentration.
When comparing the ratio of ROI activation, we did not find any difference between the mixtures.
Although location of the internal mammary artery is close enough to the breast coil to yield sufficient signal-to-noise ratio, an ROI within a single vessel is necessarily small.
Finally, the percentage of pixels in whole tumor ROI above this ratio of 0.93 was calculated to obtain the FHV.
In all plots, the error bars are the standard deviations across the data sets and are only shown in two representative locations for clarity Table 1 Average ratio between ROIs and whole brain at equilibrium Uncon.
The values for individual cells and dendrites were calculated as mean ratio in ROIs.
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