For the calculation method proposed by Luccioni and Reimundin et al., as shown in Table 5, the average ratio of test results and predicted ultimate torques is 0.8.
Data are expressed as a ratio of test pulse to conditioning pulse PS amplitude.
Paired-pulse inhibition (ratio of test to conditioning MEP) was averaged per block.
The copy number of the test locus is then estimated from the ratio of test to reference products.
The variable used for analysis is the normalized average of the log2 ratio of test sample over reference sample.
The signals were scored according to two parameters; signals per cell and ratio of test probe to control probes.
The gene of interest/endogenous standard ratio of test samples was expressed in relation to the ratio found for control cell lines overexpressing the gene tested.
Fluorescence profiles, representing the ratio of test : reference DNA, were plotted along the length of each chromosome against the corresponding DAPI-banded ideogram (Breen et al, 1999b).
The peak areas were extracted using GeneMapper software (Applied Biosystems) and the ratio of test locus to reference locus was calculated for each sample.
We chose to analyse the results on the basis of the fluorescence ratio (FR) calculated as the normalized ratio of test to reference DNA, using the simple ratio rather than the logarithmic ratio.
An ROC-AUC validity statistic of 0.80 (null hypothesis AUC 0.69) can be detected with 80% power assuming a 3 1 ratio of test positive (competent to consent) and test negative children.
