Wild type Y. pestis KIM D27 with or without recombinant pACYCdapA were combined in a 1∶1 ratio (doses ranging from 1,000 to 13,000 CFU each strain) and injected intravenously into BALB/c or C57BL/6 mice in a 100 µl volume.
Characteristics of patients, including age, male/female ratio, doses of prednisolone, disease history, etc, between SR and SS groups were coincident.
Furthermore, when simultaneously express multiple different proteins, mRNA vectors allow for greater flexibility and control over stoichiometric ratios, dose titrations, and complete silencing of expressions.
As demonstrated in Table 6, all test doses of the extract significantly reduced the intestinal weight ratio in dose dependent manner.
Stochastically, only a small fraction of cells receive the optimal reprogramming factor ratio and dose for cell fate reprogramming.
The mean ratio of dose escalation for NMS patients was 1.4.
Allocation was stratified by TNF inhibitor using block randomisation in random sized blocks (block size 3-12), and in a ratio of dose reduction versus usual care of 2 1.
Different factors such as heterogeneous patient material, ω-6: ω-3 ratio, EFA dose or duration of treatment may have decreased the effect size, if it existed.
However, the ratio of dose at the Bragg peak to that in the entrance region is higher for heavy ions [ 2].
Dose enhancement factors (DEFs) were calculated as the ratio of doses leading to equal levels of cell survival in the presence and absence of GNPs.
