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Counts were derived from both ROIs in order to calculate the osteoblastic activity ratio (count for the lesion/count for the contralateral side).
CGP: Gene-sets represent expression signatures of genetic and chemical perturbation; OR: odds ratio; #: count.
Criteria were based on both individual ratio count and individual enrichment ratios in comparison to aggregate ratios.
Protein quantification was done with a peptide ratio count of, at least, 2. Phosphopeptide identification was performed applying similar settings as in the total protein analysis.
Unique and razor peptides were considered for quantification with a minimum ratio count of 1. Retention times were recalibrated based on the built-in nonlinear time-rescaling algorithm.
Quantification was carried out using the label-free quantification algorithm implemented in MaxQuant using a minimal ratio count of 2 and the "match between runs" option enabled.
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What ratio counts as high is a matter of debate, but 1995 is a good starting point.
And because of the way that Reinhart and Rogoff weighted their samples, New Zealand's one year of very negative growth with a high debt-to-G.D.P. ratio counted as much in their calculations as the U.K.'s nineteen years of moderately positive growth — 2.4percentnt per annum — with high debts.
To obtain the plasma-to-whole blood ratio, counts from plasma and blood pellet were averaged for weight.
A total of 23 miRNAs were found to have roughly equivalent (0.75 2.2 relative ratio) counts generated from each arm of the pre-miRNA in at least one of the libraries (Table S5).
Quantification via normalized H/L ratios was based on minimum of 3 peptide ratio counts.
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